(Albany, United States) As per DelveInsight’s assessment, globally, the Anaplastic Astrocytoma Pipeline constitutes 15+ key companies continuously working towards developing 15+ Anaplastic Astrocytoma Pipeline treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analysis DelveInsight.
In the Anaplastic Astrocytoma Pipeline Report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, Anaplastic Astrocytoma NDA approvals (if any), and product development activities comprising the technology, Anaplastic Astrocytoma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
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Key Takeaways from the Anaplastic Astrocytoma Pipeline Report
Anaplastic Astrocytoma Overview
Anaplastic Astrocytoma is a rare malignant brain tumor. Astrocytomas are tumors that develop from certain star-shaped brain cells called astrocytes.
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Anaplastic Astrocytoma Emerging Drugs Profile
Eflornithine, also known as α-diflurormethylornithine (DFMO), selectively targets and irreversibly inhibits ornithine decarboxylase (ODC), an enzyme essential for polyamine synthesis, and DNA and RNA function. Unlike multi-targeted tyrosine kinase inhibitors on the market or in development, eflornithine targets only one specific enzyme, ODC. In animal studies, eflornithine has been shown to inhibit the growth of malignant tumors, including intra cerebral mid- and high-grade gliomas. Eflornithine administration has also been shown to potentiate the anti-tumor activity of other chemotherapy agents. In single-arm and controlled, randomized clinical trials, eflornithine oral solution increased survival in patients with both newly diagnosed and recurrent anaplastic glioma. The primary and reversible side effects of eflornithine were diarrhea and hearing impairment.
Zotiraciclib is a potent oral spectrum selective kinase inhibitor for the treatment of cancer. It was discovered in Singapore by S*BIO Pte Ltd and falls under the category of small molecule macrocycles. It crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9. In October 2021, Cothera Bioscience Inc. and Adastra Pharmaceuticals Inc., announced a definitive agreement under which Cothera has acquired zotiraciclib (ZTR).
Anaplastic Astrocytoma Pipeline Therapeutics Assessment
There are approx. 15+ key companies which are developing the therapies for Anaplastic Astrocytoma. The companies which have their Anaplastic Astrocytoma drug candidates in the most advanced stage, i.e. phase III include, Orbus Therapeutics.
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Anaplastic Astrocytoma Drug and Companies
Anaplastic Astrocytoma Therapeutics Assessment
Some of the Companies in the Anaplastic Astrocytoma Therapeutics Market include-
Orbus Therapeutics, Cothera Bioscience, Celgene, Wayshine Biopharm, Inc., OncoSynergy, AEterna Zentaris, Oncoceutics, DNAtrix, Novartis Pharmaceuticals, Curis, Inc., Everfront Biotech Co., Ltd., Pfizer, Kazia Therapeutics Limited, Bayer, Geneos Therapeutics, Cellix Bio, Mustang Bio, Deciphera Pharmaceuticals, Aveta Biomics, and others.
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Scope of the Anaplastic Astrocytoma Pipeline Report
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