Epidemiology and Changing Market Dynamics of Propionic Acidemia in the Seven Major Markets

May 20 02:00 2021
Epidemiology and Changing Market Dynamics of Propionic Acidemia in the Seven Major Markets


Propionic Acidemia Market” report has been added to DelveInsight


Propionic Acidemia Overview

Propionic Acidemia is an inherited disorder in which the body is unable to process certain parts of proteins and lipids (fats) properly. It is an autosomal recessive disorder and is classified as an organic acid disorder, which arises due to an abnormal rise in levels of particular acids known as organic acids.


Propionic Acidemia Market

DelveInsight’s “Propionic Acidemia – Market Insights, Epidemiology, and Market Forecast-2030” report delivers an in-depth understanding of the Propionic Acidemia, historical and forecasted epidemiology as well as the Propionic Acidemia market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.


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Propionic Acidemia Market: Regions Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan


Propionic Acidemia Key Players

  • Moderna Tx
  • HemoShear
  • And many others


Propionic Acidemia Drugs

  • mRNA-3927
  • HST5040
  • And many others


Propionic Acidemia Market Report

Mutation in genes which are involved in the production of propionyl-CoA carboxylase, leads to Propionic Acidemia. These genes are: PCCA gene which encodes information to produce alpha subunit of propionyl-CoA carboxylase, and the PCCB gene which encodes information to produce Beta subunit of propionyl-CoA carboxylase, specifically, the beta subunit of this enzyme.


Propionic Acidemia Symptoms

In most cases, within a few days after birth the features of propionic acidemia become apparent. The most typical symptoms are loss of appetite, poor feeding, vomiting, weak muscle tone (hypotonia), and lack of energy (lethargy).


Propionic Acidemia Treatment

Presently, there is no specific treatment for Propionic acidemia. Management of the individuals with the disease happens through dietary management and liver transplantation in some cases.

Treatment options include: aggressive treatment of decompensation events, special protein managed diet, medications such as carnitine, avoidance of stressors (such as fasting or illness) that can lead to a decompensation event and in some cases liver transplant. The complete management of Propionic Acidemia involves treating manifestations, preventing primary manifestations and secondary complications, monitoring, avoiding certain agents/circumstances and evaluation of relatives at risk.


Propionic Acidemia Market Insights

The spectrum of propionic acidemia (PA) ranges from neonatal-onset to late-onset disease. Neonatal-onset PA, the most common form, is characterized by a healthy newborn with poor feeding and decreased arousal in the first few days of life, followed by progressive encephalopathy of unexplained origin. Whereas, individuals with late-onset PA remain asymptomatic and suffer a metabolic crisis under catabolic stress (e.g., illness, surgery, fasting) or may experience a more insidious onset with the development of multiorgan complications including vomiting, protein intolerance, failure to thrive, hypotonia, developmental delays or regression, movement disorders, or cardiomyopathy.


Propionic Acidemia Treatment Market

The current treatment regimens in Propionic Acidemia are focused on managing symptoms and providing support. There is no specific therapy or cure for the disease. The optimal management of patients is best achieved by a team of specialists involved in the care of people which include; Nutritionist, Genetics professional, Developmental specialist, Neurologist, Physical therapist and occupational therapist.


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Table of content

1. Key Insights

2. Executive Summary of Propionic Acidemia

3. Competitive Intelligence Analysis for Propionic Acidemia

4. Propionic Acidemia: Market Overview at a Glance

5. Propionic Acidemia: Disease Background and Overview

6. Patient Journey

7. Propionic Acidemia Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Unmet Needs

10. Key Endpoints of Propionic Acidemia Treatment

11. Marketed Products

12. Emerging Therapies

13. Propionic Acidemia: Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Propionic Acidemia

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight


Propionic Acidemia Market Research Methodology

The objective of updating DelveInsight coverage is to ensure that it represents the most up-to-date vision of the industry possible. The DelveInsight is a fully integrated solution for comprehensive intelligence on various pharmaceutical products, both in the market and in the pipeline, across the globe.


Why should you buy this report?

  • The report will help in developing business strategies by understanding trends shaping and driving the Propionic Acidemia market
  • To understand the future market competition in the Propionic Acidemia market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Propionic Acidemia in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Propionic Acidemia market
  • To understand the future market competition in the Propionic Acidemia market


About Us

DelveInsight is a Business Consulting and Market research company, providing expert business solutions for life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.



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